Partial Cellular Reprogramming

Controlled expression of Yamanaka factors to rejuvenate tissues without losing cellular identity.
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Partial Cellular Reprogramming

A therapy that transiently activates genes associated with embryonic stem cells to reset the 'epigenetic age' of adult cells. The goal is to restore youthful function and regenerative capacity to organs like the heart, liver, and skin, without causing the cells to revert fully to a stem cell state (which would cause cancer).

TRL
4/9Formative
Impact
5/5
Investment
5/5
Category
Applications

Connections

Software
Cellular Reprogramming Simulators

Software predicting OSK/OSKM induction thresholds, rejuvenation windows, and reprogramming risk profiles.

TRL
4/9
Impact
5/5
Investment
4/5
Applications
Applications
Telomerase Gene Therapy

Controlled activation of telomerase to extend cellular replicative capacity without triggering cancer.

TRL
3/9
Impact
5/5
Investment
5/5
Applications
Applications
Therapeutic Plasma Exchange

Blood renewal protocols that remove pro-aging factors and introduce youthful circulating factors.

TRL
5/9
Impact
4/5
Investment
4/5
Applications
Applications
On-Demand Organoid Transplantation

Patient-specific mini-organs grown from stem cells to rejuvenate or replace failing tissues.

TRL
4/9
Impact
5/5
Investment
4/5
Hardware
Hardware
Whole-Organ Regeneration Bioreactors

Perfusion bioreactors that repair, rejuvenate, and recellularize donor or patient organs ex vivo.

TRL
5/9
Impact
5/5
Investment
5/5
Hardware
Programmable Cell Factories

Microfluidic hardware that grows, differentiates, or edits stem cells for rejuvenation use.

TRL
4/9
Impact
4/5
Investment
3/5

Envisioning is an emerging technology research institute and advisory.

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2011 — 2026

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