
Geography: Americas · South America · Brazil
Brazil's tropical disease burden — dengue, Zika, chikungunya, Chagas disease, leishmaniasis, malaria — drives one of the world's most active research ecosystems for neglected tropical diseases. Fiocruz, Butantan, and university research networks maintain diagnostic development, drug discovery, and vaccine pipelines.
Fiocruz produces diagnostic reagents for HIV, dengue, Chagas, and leptospirosis at national scale. Butantan developed a dengue vaccine candidate (Butantan-DV) in Phase III trials. The institutions train researchers from across Latin America and Africa.
The expertise is uniquely Brazilian because the diseases are: countries in the Global North have limited incentive to invest in diseases that don't affect their populations. Brazil's research institutions fill a gap that the global pharmaceutical industry largely ignores, serving 1+ billion people in tropical regions worldwide.