Continuous cuffless blood pressure monitoring uses non-invasive sensors to measure blood pressure without the need for inflatable cuffs, enabling comfortable, continuous monitoring throughout daily activities. These systems typically use photoplethysmography (PPG) sensors that measure blood volume changes in arteries, combined with algorithms that derive blood pressure from pulse wave analysis, pulse transit time, and other cardiovascular signals. The calibration-free approach eliminates the need for periodic recalibration against traditional cuff measurements.
The technology enables 24/7 blood pressure tracking, providing insights into blood pressure patterns throughout the day, during sleep, and in response to activities and stress. Continuous monitoring can detect hypertension, identify blood pressure variability, and help manage cardiovascular health more effectively than occasional spot measurements. The cuffless design is comfortable for extended wear, doesn't interrupt sleep, and allows users to monitor blood pressure during normal activities. This technology is particularly valuable for individuals with hypertension, cardiovascular conditions, or those at risk, enabling proactive health management and early detection of concerning patterns. The FDA approval for over-the-counter use makes this technology accessible for consumer health monitoring.
Develops a clinically validated optical bracelet for 24/7 continuous blood pressure monitoring without cuffs.
Provides a wearable patch and wrist monitor for continuous non-invasive monitoring of blood pressure and other vitals.
Develops the LiveOne, a wrist-worn, cuff-free device for continuous blood pressure monitoring using nano-sensor technology.
Develops the CART-I ring, a ring-type medical device for continuous health monitoring including blood pressure.
Software solution that uses smartphone cameras (optical sensors) to measure blood pressure via fingertip placement.
Focuses on vascular health technologies and wearable solutions (CONNEQT) for dual blood pressure monitoring.
Develops medical-grade wearables (Embrace) monitoring EDA and physiological signals.
Paper
A conformal piezoelectric microsystem for demographic-adaptive and calibration-free cuffless blood pressure monitoringNature Communications · Dec 9, 2025
Introduces a conformal and stretchable piezoelectric microsystem (CSPM) combined with a demographic-adaptive BP estimation model, enabling calibration-free, continuous BP tracking with accuracy comparable to cuff-based medical devices.
Paper
Predicting blood pressure without a cuff using a unique multi-modal wearable device and machine learning algorithmComputers in Biology and Medicine · Jun 1, 2025
Describes a multimodal device combining PPG and BioZ sensors with a Random Forest model to improve cuffless blood pressure prediction accuracy across different skin tones.
